Open Access Journal of Biomedical Science | Biomedscis

Management Approach for Microscopic Polyangiitis: A Case Report by Mohammed Al Azzawi* in Open Access Journal of Biomedical Science (OAJBS) Microscopic polyangiitis is a small vessel necrotizing vasculitis. It usually exhibits its manifestation through inflammation on the kidneys, it also presents with an extrarenal systemic involvement such as the lungs, musculoskeletal systems, central or peripheral nervous system, and skin manifestations. Laboratory markers show an elevation in the inflammatory markers and Myeloperoxidase-Antinuclear Cytoplasmic Antibody. Kidney involvement usually manifests in the form of rapidly progressive pauciimmune glomerulonephritis. The Lung present at the range of fleeting local infiltrates to massive hemorrhage is the setting of diffuse alveolar hemorrhage. Patients generally respond appropriately to induction therapy with high IV pulse-dose prednisolone plus an additional immunosuppressive agent followed with maintenance therapy with an oral immunosuppr...

Distribution of Head Smudge (Helminthosporium Miyakei) of Tef Disease During Short Rainy and Main Cropping Seasons in Some Parts of Oromia and Southern Nation Nationality and People Regions of Ethiopia by Ashenafi Gemechu Degete* in Open Access Journal of Biomedical Science (OAJBS) Head smudge of tef caused by Helminthosporium miyakei is among the most economically important disease causing significant economic losses of yield and quality. To investigate the distribution of this disease in belg (short rainy) and main (long rainy) seasons in Oromia and SNNP regions, disease assessment survey was conducted in 2019 main season and 2020 belg season from September 25 to May 22-25 G. C. Tef fields were randomly selected at 5-10 km intervals along accessible routes. The result showed head smudge prevalence and intensity varied across locations within the zone and among districts. From a total of forty-two fields surveyed during main and belg seasons (twenty-three fields during the main seas...

Studying of Anthocyanins of Cerasus Vulgaris Mill. Species Spreading in the Territory of Nakhchivan Autonomous Republic and its Application as pH Indicator by Rahimova Sura Ali* in Open Access Journal of Biomedical Science (OAJBS) The color of anthocyanins changes not only according to their chemical structure, but also according to the pH and concentration of the medium. The most influential are their pH values for color and consistency. Extraction and purification of anthocyanin pigments from Cerasus vulgaris Mill. species was successfully carried out. According to the obtained Rf values and UV wavelengths, it was determined that component A was cyanidin 3-sophoroside, component B was cyanidin 3-glucosylrutinoside, component C was cyanidin 3-glucoside, and component D was cyanidin 3-rutinoside. Also, UV spectrum of components were measured. The Rf value in the solvent system of component A was 0,26 and 0,18 in the II, and the UV wavelength was 524, 529, 530 nm, respectively, accordi...

Higher Education During the Pandemic: The Experience of Ukraine and Uzbekistan by Eshniyazov Rustam* in Open Access Journal of Biomedical Science (OAJBS) The coronavirus pandemic is having a very big impact on higher education. Higher education is forced to revise the forms of classes and introduce distance learning. The object of research in this article is the process of introducing distance education in higher education institutions as a result of the spread of the coronavirus pandemic. The subject of the study was the advantages and threats in the development of distance education. The article highlights the characteristic features of distance learning: distance learning occurs remotely using information and communication technologies in individual or collective form in synchronous (asynchronous) mode; interactively. Mandatory requirements for the organization of distance learning are considered. The article describes the problems that arise in higher education institutions when ...

Long COVID-19 Syndrome Precaution and Management by Abdel-Fattah HMM* in Open Access Journal of Biomedical Science (OAJBS) COVID-19 virus defined as illness caused by a novel coronavirus which first discovered in Wuhan City, China and on January 30, 2020, the WHO awarded the global health emergency. This is a review of COVID-19’s highly effects on almost all the organs and how we precaution and management as the COVID-19 causes many systemic abnormalities like inflammation, endotheliosis, vasoconstriction, hypercoagulability, edema and Lymphocytopenia, with elevated D-dimer, and disseminated intravascular coagulation. Deep vein thrombosis and venous, thrombosis with pulmonary embolization, systemic and pulmonary arterial thrombosis, embolism is reported, ischemic stroke changes, and myocardial infarction are reported also. it can lead to acute coronary syndrome, with heart failure and myocarditis, arrhythmias. Kidney affection was usually secondary to systemic all over disturbances. ...

Effects of Genotype by Weaning Age Interaction on Growth Traits in Rabbit by Mohamed Ragab* in Open Access Journal of Biomedical Science (OAJBS) Weaning age is an important event that affects the growth and health of weaned animals which has many impacts on mortality and growth traits. An experiment was conducted to study genotype (G) and weaning age (WA) interaction (G×WA) effects on growth traits of the animals belonged to two lines of rabbit (APRI and V line) reared under Egyptian conditions. Multiparous rabbit does were serviced to obtain 225 litters with 1800 young rabbits at weaning. The weaning ages ranged from 26 to 43 days where the young rabbits were weaned at different ages (≥28d (WA 1 ); 28 < T ≥ 35d (WA 2 ); 35 < T ≥ 40d (WA 3 ) and 40<Td (WA 4 )). Body weight from 4 to 16 weeks of age (BW t ) and corresponding average daily gain (ADG t1-t2 ) were measured. APRI rabbit line was significantly heavier body weight compared to V line at the different ages. At the end ...

Clear Cell Carcinoma with Neck Metastasis: A Case Report by Fred Delgado Ricardo* in Open Access Journal of Biomedical Science (OAJBS) Clear cell carcinoma represents only 3% of all adult malignant tumors worldwide and when we include single metastases to the neck, we find an incidence of only 0.09% -0.4%. Only isolated anecdotal cases have been reported in the literature. The objective of presenting this case is to describe the clinicopathological manifestations, as well as the diagnosis of metastases to a very rare site in clear cell renal carcinoma. We present the case of a 64-year-old female patient, of Guatemalan nationality, with a personal history of kidney stones, acute kidney injury 2 years ago, bilateral grade III venous insufficiency, chronic hypokalemias for 15 years and a family history of breast cancer (mother), cervical cancer (grandmother), pulmonary fibrosis (father). Currently, the treatment of clear cell renal cell carcinoma metastases is primarily palliative; how...

Once upon a Time ERAS Principles and Future Perspectives in Emergency Surgery by Marco Scatizzi* in Open Access Journal of Biomedical Science (OAJBS) Enhanced Recovery After Surgery (ERAS) is multimodal care approach that has revolutionized clinical practice in the field of elective Colo-rectal surgery; thanks to the scientific evidence acquired, ERAS has become standard approach for elective Colo-rectal cancer. As regards the application of an ERAS program in emergency Colo-rectal surgery, the available literature is still poor, and the few data available derive from studies of moderate quality. The first available data of literature suggest the safety, feasibility, and benefits of applying a modified ERAS protocol in abdominal Colo-rectal and small bowel surgery in emergency regime. In fact, the adoption of a modified ERAS program is associated with a lower incidence of complications and reduction in post-operative hospitalization without increasing the risk of readmission or re-o...

Overexpression of PTGS2/COX-2 Gene Induces Angiogenesis, Metastasis and Invasion in TNBC In Vitro Cell Lines by Overexpressed Fzd-6 Wnt/ Ca++ Signaling Pathway by Vikas Kumar Maurya* in Open Access Journal of Biomedical Science (OAJBS) Cancer remains the scourge of mankind. After lung cancer, breast cancer is the second most common form of cancer. Breast cancer is the most common cancer in Indian women accounting for 27.7%with 1,62,468 newly detected cases and 87,090 deaths in 2018. Triple-negative breast cancer (TNBC) prevalence in India varies between 27 to 35% of total breast cancer [1]. TNBC refers to a subgroup of breast cancer identified by the lack of ER (Estrogen Receptor), PR (Progesterone Receptor) & HER (Human Epidermal Growth Factor Receptor). ER-/PR-/HER2- status is the main reason behind poor prognosis, failure of targeted therapy against these receptors like (Herceptin) and increased aggressiveness at an advanced stage [2]. Research paper and literature suggest that ...

State of International Medical Graduates Applying for Training in the United Kingdom by Adeel Abbas Dhahri* in Open Access Journal of Biomedical Science (OAJBS) International Medical Graduates (IMGs), after obtaining their basic or higher medical qualification, relocate to the United Kingdom (UK) for further experience in the standard system and obtain a postgraduate qualification. As misunderstanding and misconception is expected, not all find themselves lucky to obtain career progression. Despite UK National bodies trying to help IMGs transition, there lies an inability to achieve the required specification despite exhausting and tireless effort for the training selection process. Failing this may cause a psychological impact on the IMGs, resulting in untoward decisions like changing the desired specialty, seeking an alternative route to achieve a postgraduate qualification or opting out of a medical career. Targeted and career-oriented mentorship plays an essential role in profes...