Relationship of Liver Enzyme Levels with the Clinical Course of Covid-19: OAJBS Publishers

Relationship of Liver Enzyme Levels with the Clinical Course of Covid-19 by Harun Tolga DURAN* in Open Access Journal of Biomedical Science (OAJBS)

Introduction: SARS-CoV-2 / COVID-19 infection, which can affect many systems in the human body, can cause organ dysfunction. High liver serum enzymes can be found in COVID-19 patients, and many factors cause this stop. Patients with high levels of liver enzymes that require invasive mechanical ventilation during their follow-up were examined, and it was aimed to determine whether it was among the predictive indicators of mortality.

Materials and Methods: Patients infected with COVID-19 who were hospitalized in the intensive care unit between March 30 and December 1, 2020 according to the criteria of hospitalization in the intensive care unit, clinical trials such as age, gender, length of stay, additional diseases, liver enzyme levels and whether invasive mechanical ventilation is required their characteristics were recorded and analyzed retrospectively and compared.

Results: Data were collected from 111 patients whose liver enzyme levels were measured from 131 patients included in the study. It was found that aspartate transaminase, alanine aminotransferase, and gamma-glutamyl transferase levels were statistically higher in the invasive mechanical ventilation group compared to the patients who did not undergo invasive mechanical ventilation.

Conclusion: Alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase levels were statistically higher in COVID19-infected patients who were treated in intensive care and undergoing invasive mechanical ventilation. These enzymes are easily accessible and are shown among predictive values in mortality.
https://biomedscis.com/fulltext/relationship-of-liver-enzyme-levels-with-the-clinical-course-of-covid-19.ID.000391.php

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