Evaluation of the effect relationship of Genetically Parkinson’s Disease (PD) with Cinnamon in Mice: OAJBS Publishers

Evaluation of the effect relationship of Genetically Parkinson’s Disease (PD) with Cinnamon in Mice by Ali Ahmadi* in Open Access Journal of Biomedical Science (OAJBS)

Parkinson’s disease (PD) is a neurodegenerative disease characterized by the gradual damage and destruction of nerve cells in the black body of Nigra pars compacta (SNc), which leads to impaired movement and is accompanied by tremors, stiff muscles and poor balance. Because PD is a progressive disease, the symptoms start gradually, starting on one side of the body and affecting the other. PD-related disorder and disability require a multidisciplinary approach to effective management to maintain daily activity and life expectancy. It has been shown that cinnamon can play a role in the treatment of this disease. Mehraein et al. In an article measuring the effects of cinnamon on mice with Parkinson’s, cinnamon acts as a powerful free radical scavenger. Cinnamon and its derivatives, cinnamaldehyde act as a powerful antioxidant and anti-inflammatory. Cinnamon prevents the accumulation of a protein called tau in the brain, which is a sign of Alzheimer’s disease. Cinnamon is metabolized in the liver to sodium benzoate so it can cross the blood-brain barrier. These findings show that cinnamalde is an antioxidant. Normal SNc neurons may protect against Parkinson’s disease.
https://biomedscis.com/fulltext/evaluation-of-the-effect-relationship-of-genetically-parkinsons-disease-pd-with-cinnamon-in-mice.ID.000394.php

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