Histopathologic Finding and Pathophysiology Pathway of Moluskum Kontangiosu: OAJBS Publishers

Histopathologic Finding and Pathophysiology Pathway of Moluskum Kontangiosum by Nanda Rachmad Putra Gofur* in Open Access Journal of Biomedical Science (OAJBS)

Molluscum contagiosum is endemic in densely populated communities, poor hygiene, and poor areas. This disease mainly affects children, adults with active sexual activity and immunodeficiency status. Transmission can be through direct contact with active lesions or autoinoculation, indirect transmission through sharing personal tools such as towels, razors, hair clippers and transmission through sexual contact. The prevalence of Molluscum contagiosum in the world varies. In the US it is 33%, in Mali 3.6%, in Australia the overall seropositivity rate is 23%, in East Africa it is 52% in children aged 2 years. The incidence of molluscum contagiosum worldwide is estimated at 2% - 8%, with a prevalence of 5% - 18% in HIV/AIDS patients. Molluscum contagiosum virus type-1 (MCV-1) was the most common subtype found in patients, whereas MCV-3 was rare. For example, analysis of 106 clinically isolated MCVs indicated the presence of MCV-1, -2, and -3 in an 80:25:1 ratio. In addition, MCV-2 was found to be more common in adults.
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