Efficacy of Letrozole as Maintenance Therapy for Ovarian Cancer: OAJBS Publishers

Efficacy of Letrozole as Maintenance Therapy for Ovarian Cancer by Juan Carlos Rivera Acosta* in Open Access Journal of Biomedical Science (OAJBS)

Ovarian cancer is a persistent disease with periods of recurrence. Surgery with subsequent chemotherapy is not sufficient to stop the disease. The aim of this study is to establish whether letrozole applied as maintenance therapy can prolong life without progression. Thanks to exposure of estrogen receptors in ovarian cancer cells, hormonal therapy provides an alternative treatment method. Aromatase inhibitors block synthesis of estrogen and prevent progression of ovarian cancer. More advantages are observed when using aromatase inhibitors (letrozole) in low-stage serous and endometrioid ovarian cancer. However, further investigations are needed to better evaluate this maintenance treatment.
https://biomedscis.com/fulltext/efficacy-of-letrozole-as-maintenance-therapy-for-ovarian-cancer.ID.000320.php

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