Medulloblastoma Associated with Brucellosis and its Mortality: What is Known?: OAJBS Publishers

Medulloblastoma Associated with Brucellosis and its Mortality: What is Known? by Andrés Iván Ramírez Montes* in Open Access Journal of Biomedical Science (OAJBS)

Background: Brucellosis is an infectious disease caused by Brucella species, being considered a zoonotic disease, with high incidence rates. Medulloblastoma is a brain tumor, having its origin in the fourth ventricle, which is a precursor of granular cells in the outer germ layer.
Methodology: A narrative review was carried out through various databases from January 2011 to May 2021; the search and selection of articles was carried out in journals indexed in English. The following were used as keywords: Medulloblastoma; Brucellosis; Glioblastoma; Mortality; Neurobrucellosis.
Results: Medulloblastoma has been widely associated with Brucella infection, with possible progression and dissemination associated with the secretion of large amounts of exosomes, which is stimulated by this microorganism, presenting characteristics of drug resistance, metastasis, invasion, angiogenesis and remodeling of the microenvironment. Exosomes being a possible approach in its diagnosis and treatment. Conclusion: The present review offers a close association between medulloblastoma, glioblastomas, gliomas, metastatic carcinomas, and Brucella infection.
https://biomedscis.com/fulltext/medulloblastoma-associated-with-brucellosis-and-its-mortality-what-is-known.ID.000299.php

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