Clinical Improvement in COVID-19 After Use of Ivermectin: A Case Series: OAJBS Publishers

Clinical Improvement in COVID-19 After Use of Ivermectin: A Case Series by Ayanfe Omololu* in Open Access Journal of Biomedical Science (OAJBS)

Background: The Coronavirus disease 2019 (COVID-19) pandemic continues unabated worldwide, with a paucity of effective medications against the disease. Ivermectin has been shown to inhibit in-vitro replication of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), with several studies demonstrating clinical effectiveness. We report a case series of COVID-19 patients with rapid symptomatic improvement after commencing Ivermectin.

Case Presentation: Consecutive COVID-19 patients admitted in our facility between September and November 2020 received Ivermectin plus standard of care and followed up till clinical improvement or outcome (survived or died). Nine of our patients received Ivermectin plus standard of care during this period, with significant clinical improvement noted across all categories of patients, which was noted ≤3 days after commencement in 3(37.5%) and >3 days in 5(62.5%). Eight (88.9%) of our patients survived, with 1(11.1%) death.

Conclusion: There is an urgent need for local clinical trials to assess Ivermectin’s effectiveness especially in resource poor areas.
https://biomedscis.com/fulltext/clinical-improvement-in-covid-19-after-use-of-ivermectin-a-case-series.ID.000298.php

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