Aqueous Extracts: An Alternative in the Control of the Intermediate Host of Schistosomiasis: OAJBS Publishers

Aqueous Extracts: An Alternative in the Control of the Intermediate Host of Schistosomiasis by Keyla Nunes Farias Gomes* in Open Access Journal of Biomedical Science (OAJBS)

Schistosomiasis is a parasitic disease caused by worms of the genus Schistosoma. Some substances are used to control the intermediate host, being a strategy to prevent the risk of infection and re-infection of the disease. According to the WHO, the recommended substance is Niclosamide; however, it presents toxicity in non-target organisms. Aqueous extracts are being increasingly studied as a potential molluscicide in combating schistosomiasis. The aqueous extract of Moringa oleifera flowers was used to evaluate the molluscicidal activity in Biomphalaria glabrata. This extract caused lethality in adult molluscs, obtaining a lethal concentration 50 = 2.37 mg/mL. In the second aqueous extract, fruits of the species Randia nilotica were used on molluscs of the species Biomphalaria pfeifferi and Bulinus truncatus. These extracts showed molluscicidal activity on both molluscs used in the experiments. In the third aqueous extract, they used leaves of the species Anagallis arvensis to test the molluscicidal action on molluscs of the species Biomphalaria alexandrina. It was possible to obtain lethal concentrations, with lethal concentration 50 = 37.9 mg/L and lethal concentration 90 = 48.3 mg/L. In the fourth aqueous extract, they used the seeds of the species Moringa oleifera to evaluate the molluscicidal activity in molluscs of the genus Bulinus. These seeds showed molluscicidal action, but they were not in accordance with what is recommended by the WHO. According to the experiments carried out with aqueous extracts, it can be seen that there are many studies using these methodologies as a form of control for schistosomiasis. Some criteria are essential to obtain a low-cost aqueous extract. It is essential to emphasize that this methodology could be used by the government to control the intermediate host of schistosomiasis in less favored areas, where the population itself would have access to inputs using accessible technological resources.
https://biomedscis.com/fulltext/aqueous-extracts-an-alternative-in-the-control-of-the-intermediate-host-of-schistosomiasis.ID.000302.php

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