Immune Checkpoint Inhibitors for Esophageal Cancer: OAJBS Publishers

Immune Checkpoint Inhibitors for Esophageal Cancer by Shun Yamamoto* in Open Access Journal of Biomedical Science (OAJBS)


Esophageal cancer (EC) is the seventh most common cancer, and patients with advanced EC have a poor prognosis. Recently, nivolumab and pembrolizumab, two immune checkpoint inhibitors (ICIs) that inhibit programmed cell death protein 1, have begun to be used for the treatment of advanced esophageal squamous cell carcinoma (ESCC). Based on the ATTRACTION-3 and KEYNOTE-181 trials, the use of nivolumab and pembrolizumab (only in programmed cell death ligand 1-positive cases) was approved for treatment by the US Federal Drug Administration for the treatment of patients with advanced ESCC. In addition, the CheckMate-577 and the KEYNOTE-590 trials have shown survival benefits for postoperative nivolumab in patients with resectable EC and for first line pembrolizumab plus doublet chemotherapy in patients with advanced EC, respectively. Many trials to evaluate ICI-containing treatments are ongoing, and these new treatments are expected to improve the clinical outcomes of patients with EC.
https://biomedscis.com/fulltext/immune-checkpoint-inhibitors-for-esophageal-cancer.ID.000267.php

To Know More About Open Access Journal of Biomedical Science Please Visit: Biomedscis

Are Click on:  https://Biomedscis.Com/

Comments

Post a Comment

Popular posts from this blog

Facile Synthesis of Chitosan Nanoparticle with Different Features and Histopathological Ultrastructural Study on The Effect of Its Bio-complex with Bovine Serum Albumin: OAJBS Publishers

Image
Facile Synthesis of Chitosan Nanoparticle with Different Features and Histopathological Ultrastructural Study on The Effect of Its Bio-complex with Bovine Serum Albumin in Mice Liver by Maged El-Kemary* in Open Access Journal of Biomedical Science (OAJBS)   We have synthesized chitosan nanoparticles (CS-NPs) with different characteristics using ionic gelation method. Results showed that the synthesized CS-NPs with different concentrations of trisodium polyphosphate (TPP) are irregular – spherical shaped with narrow size distribution and high stability. The microporous chitosan was also synthesized with new features characterized with different techniques as SEM, EDX, FTIR and BET. The synthesized microporous chitosan has a surface area and pore volume of 245.571m 2 /g and 0.155cm 3 /g respectively. Its microporous surface is functionalized with carboxyl and amine groups. Histopathological and ultrastructural studies of mice liver were performed using optical and scanning electron m...
Read more

Carlos Gravato | Biomedscis Editor

Image
Biomedscis  Honorable Editors Name: Carlos Gravato Department: Department of Science University: University of Lisbon Country: Portugal Completed PhD in Biology (2002). Working as Assistant Professor in FCUL and CESAM, University of Lisbon, Portugal. Biomarkers; Animal Physiology; Cell Biology; Neurobiology; Animal Behavior; Ecotoxicology; Adaptation Biology To Know More About Open Access Journal of Biomedical Science   Please Visit:  Biomedscis Are Click On:   Https://Biomedscis.com
Read more

Review on Analysis of Breast Tumor with Methods of Treatment: OAJBS Publishers

Image
Review on Analysis of Breast Tumor with Methods of Treatment by Nagham Mahmood Aljamali* in Open Access Journal of Biomedical Science (OAJBS) Breast malignance is the greatest public in ladies, with a high incidence in North America and Eastern Europe, medium in Southern Europe and the Middle East and low in the Far East. Breast malignance is the second most common malignance in the world after lung malignance, and since it happens a lot, the doctors asked the women to examine themselves by themselves, in order to discover the signs of the disease early before it spreads. It is possible that this disease can be treated after being diagnosed by a specialized doctor and determining the type of tumor in the breast, and the surgeon removes the breast completely and starts chemotherapy about 6 doses, then radiotherapy, how many sessions will be determined by the doctor, and then hormonal therapy, a medicine called Tamoxafin or any medicine determined by the doctor, and it is possible. This ...
Read more