Open Access Journal of Biomedical Science | Biomedscis

Mortality by Lesions Caused by Transit on the TriCountry Border Shared by Brazil, Paraguay and Argentina by Ludmila Mourão Xavier Gomes in Open Access Journal of Biomedical Science Purpose: To analyse the lesions caused transit (LCTs) mortality trend on the tri-country border shared by Brazil (Paraná), Argentina and Paraguay. Methods: A retrospective time-series study between 1996 and2015 carried out in 17 municipalities of Paraná, located on the border with Paraguay and Argentina in comparison with non-frontier region. There was a calculation of mortality rates and verified the mortality trend through polynomial regression. https://biomedscis.com/fulltext/mortality-by-lesions-caused-by-transit-on-the-tri-country-border-shared-by-brazil-paraguay-and-argentina.ID.000223.php To Know More About Open Access Journal of Biomedical Science Please Visit: Biomedscis Are Click On:   https://Biomedscis.Com/

Approach of Intern Doctors to Antibiotic Prescription for Sore Throat by Mohammad Abdullah in Open Access Journal of Biomedical Science Objective: While former studies have investigated the approach of general practitioners (GPs) to antibiotic prescription, there is scarce evidence on the prescription trends for young, primary care doctors despite their cardinal role in the overall practice of antibiotic administration. The research aimed to study the approach of young doctors towards antibiotic prescription for a commonly encountered ailment, sore throat. Methods and Materials: A cross-sectional study of the interns’ clinical approach was conducted at CMH Lahore Hospital. A questionnaire containing four clinical vignettes, each with various presentations of sore throat was given to interns chosen by random, convenience sampling and 80 interns with a minimum clinical experience of 6 months participated in the study. https://biomedscis.com/fulltext/approach-of-intern-doctors-to-antibiot...

Utility of Cell and Molecular Biology Research for the Diagnosis and Therapy of Oral Premalignant Lesions by Carmen-Elena Cotrutz in Open Access Journal of Biomedical Science Introduction: Premalignant oral lesions represent one of the most important risk factors for the development of oral scuamoous cell carcinoma, the sixth most common malignancy diagnosed worldwide. The characteristic phenotypic and molecular variability of these lesions condition the early identification of the risk of malignant transformation, with a significant impact on prognosis and quality of life. Accurate and complete description of cell interactions involved in the carcinogenic cascade requires the use of the results of cell and molecular biology research. In this regard, this paper aims to evaluate the intricate role of molecular markers in assessing the progression of the most common premalignant oral lesions. https://biomedscis.com/fulltext/utility-of-cell-and-molecular-biology-research-for-the-diagnosis...

Better Outcomes in High-Power Short-Duration Compared to Low-Power Long-Duration Atrial Fibrillation Ablation in One-Year Follow-Up by Fabricio Vassallo in Open Access Journal of Biomedical Science Introduction: Different results are described after atrial fibrillation ablation and multiples predictors of recurrence are well established. Objective: Evaluate and analyze if patients submitted to first time atrial fibrillation (AF) ablation with high-power short-duration (HPSD) have better outcomes compared to low-power long-duration (LPLD). Methods: Observational, retrospective study, 144 patients submitted to HPSD and LPLD ablation. HPSD: 71 patients, 50(70.42%) males, mean age 59.73 years, 52(73.24%) hypertension, 44(61.97%) obstructive apnea, 23(32.39%) arterial disease, 20(28.17%) Diabetes, and 10(14.08%) strokes. CHADS2VASC2 2.57. CT: 73 patients, 50(68.49%) males, mean age 60.7 years, 53(72.60%) hypertension, 41(56.16%) obstructive apnea, 28(38.36%) arterial disease, 14(19.17%) Dia...

Comparison of Sodium Concentration between Ham Dry Cured with NaCl and a KCl/NaCl Mixture: A Systematic Review by Reinaldo Letelier in Open Access Journal of Biomedical Science Cured products are popular in developed countries; however, due to an increased risk of cardiovascular disease, associated in part with higher sodium consumption in the human diet, it is convenient to explore alternative food preservation methods without altering the chemical properties of ham. Legs of pigs (corresponding to the pelvic member) from the same batch raised in an extensive production system were processed using the traditional method of cured ham. The left legs were cured using a treatment with NaCl (treatment A), while a mixture of NaCl / KCl (treatment B) was used for the right legs. Changes in weight, Na and K concentration, as well as pH were evaluated and compared at the end of the process. The inclusion of KCl produces a decrease in Na (p < 0.05) and an increase in K (p < 0.05). It was r...

Anticoagulation in COVID-19 “Benefit Exists But we Need Trials”: A Systematic Review by Hugo Costa in Open Access Journal of Biomedical Science The pandemic we are facing has been devastating in some regions of the globe, not only because of the rapid spread, but also because of the unpredictability form of presentation and course of the disease. In fact, COVID-19 in its most severe form (SARS-CoV-2 pneumonia) and its systemic consequences have been described by several colleagues on the ground. The variety of multiorganic consequences, particularly cardiovascular, and the little expected response to therapeutic strategies as in the case of ventilation, makes us realize that knowledge about the virus is still scarce. https://biomedscis.com/fulltext/anticoagulation-in-covid-19-benefit-exists-but-we-need-trials.ID.000216.php To Know More About Open Access Journal of Biomedical Science Please Visit: Biomedscis Are Click On:   https://Biomedscis.Com/

Comparison of Tocilizumab and Convalescent Plasma Therapy for COVID-19: A Systematic Review by Steffi Rose Mathew in Open Access Journal of Biomedical Science Background: The current pandemic referred to as coronavirus disease 2019 (COVID-19), has identified the causative respiratory pathogen as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). High viral load leads to cytokine storm (CS) and other symptoms that leads to severity, mortality and infectivity of patients. Methods: A review of databases PubMed and Google Scholar was conducted from May 25 to June 16, 2020. After exclusion of systematic reviews, studies on other treatment strategies, meta-analysis and articles not related to COVID-19 treatment, 21 clinical studies on COVID-19 infection of tocilizumab (TCZ) and convalescent plasma (CP) were identified and included. https://biomedscis.com/fulltext/comparison-of-tocilizumab-and-convalescent-plasma-therapy-for-covid-19-a-systematic-review.ID.000215.php To Know More...

Post-Transplant Cyclophosphamide in Hematopoietic Stem Cell Transplantation for Langerhans Cell Histiocytosis by Rong Liu in Open Access Journal of Biomedical Science Hematopoietic stem cell transplantation (HSCT) has the potential to cure refractory multisystem Langerhans cell histiocytosis (MS-LCH). However, a post-transplant cyclophosphamide (PTCy) regimen has never been applied for refractory MS-LCH. The objective of this article is to report the successful use of PTCy after reduced-intensity conditioning haploid HSCT in a 22-monthold girl with refractory MS-LCH and hemophagocytic lymphohistiocytosis (HLH). Her clinical symptoms were recurrent fever, polydipsia, diuresis, rash, and hepatosplenomegaly. She failed to respond to chemotherapy but was finally cured by haploid HSCT with PTCy regime. This case enriched our knowledge of the management of graft-versus-host disease prophylaxis in LCH patients, which has not been reported before. https://biomedscis.com/fulltext/post-transpla...

Rare Presentation of a Facial Giant Cell Tumor: A Case Report by Nádia AH Fortes in Open Access Journal of Biomedical Science Giant Cell Tumors (GCT) are benign bone neoplasms, of mesenchymal nature, with uncertain biological behavior, uncommonly located in the craniofacial skeleton. These tumors have a high probability of recurrence after surgical treatment. We intend to report a case of GCT of grotesque dimensions located simultaneously in the mandible, jaws, right malar bone, palatal bones, and maxillary sinus walls, in an 18-year-old melanodermic male patient with 10-years evolution, that was observed at the Central Hospital of Maputo-Mozambique. In which a radical and oncological surgical treatment would be necessary considering the cure of the patient with the lowest possible toxicity in the short and long term, preserving the function and aesthetics of the patient, without excluding periodic postoperative follow-up. In conclusion, it is a challenge to approach this specific clin...

Low-dose Aspirin for Preventing Preterm Birth: A Meta-Analysis by Fuchuan Wang in Open Access Journal of Biomedical Science Objective: Preterm birth (PTB) remains a leading cause of neonatal mortality and is a disproportionately high burden. Aspirin is increasingly used to prevent PTB, so it is necessary to further evaluate the effect of different doses of aspirin in different gestational weeks on PTB. Data Sources: A systematic literature search of the PubMed, Embase, Medline, ClinicalTrials.gov, and the Cochrane database (from database inception to 1 March 2020) for randomized controlled trials (RCTs) that examined treatment with aspirin versus placebo for PTB. https://biomedscis.com/fulltext/low-dose-aspirin-for-preventing-preterm-birth-a-meta-analysis.ID.000212.php To Know More About Open Access Journal of Biomedical Science Please Visit: Biomedscis Are Click On:   https://Biomedscis.Com/

Assessment of Maxillofacial Trauma by Facial Injury Severity Score (FISS) System by Salman Shams in Open Access Journal of Biomedical Science Objective: To assess severity of maxillofacial trauma with help of Facial Injury Severity Score (FISS) System. Subject and Methods: This is a Cross sectional study conducted at Oral and Maxillofacial Surgery Department of Liaquat University of Medical & Health Sciences, Jamshoro/Hyderabad, Pakistan from August 2017 to August 2018. Data was collected from 167 patients admitted in Oral & Maxillofacial Surgery Department, Liaquat University of Medical & Health Sciences, Jamshoro/ Hyderabad, who met inclusion criteria. The FISS score was taken as the sum of all individual scores then final score was done and grouped according to mild, moderate and severe injuries. https://biomedscis.com/fulltext/assessment-of-maxillofacial-trauma-by-facial-injury-severity-score-fiss-system.ID.000211.php To Know More About Open Access Journal of Biomedical...

The Portability of Health Care Services Between Guangdong and Macao by Zhang Rui in Open Access Journal of Biomedical Science In the context of the development of a healthy city, the use of medical electronic vouchers, the remarkable results of smoking control policy, and the relatively ideal preventive medicine and the control of COVID-19 pandemic, Macao has a sound healthcare system. According to Macao’s micro-economy and newly introduction of faculty of medicine in local university, Macao SAR Government has to coordinate medical resources with Guangdong Province in the future, in order to enable local residents to obtain more comprehensive and convenient medical services, i.e. the portability of medical services. Medical doctor resources are an important part of the medical service system and an important factor of the level of medical service. This study uses PEST as the analysis framework to summarize the factors for the development of cross-city medical care and multiple location...

Clinical and CT Features of Critically Ill Patients Requiring Ventilation Who Recovered from COVID-19 Pneumonia by Shanshan Yu in Open Access Journal of Biomedical Science Objectives: To investigate the clinical and CT features of critically ill patients requiring ventilation who early recovered from COVID-19 pneumonia. Methods: The clinical, laboratory and CT features of COVID-19 patients at Tongji Hospital in Wuhan from Jan 31, 2020, to April 20, 2020, were retrospectively analyzed. Patients who required ventilation during treatment were defined as group 1. Meanwhile, patients who received conventional oxygen inhalation therapy in the same wards were defined as group 2. The clinical characteristics and follow-up CT images were collected and compared between the two groups. https://biomedscis.com/fulltext/clinical-and-ct-features-of-critically-ill-patients-requiring-ventilation-who-recovered-from-covid-19-pneumonia.ID.000209.php To Know More About Open Access Journal of Biomedical S...