Frequency of Raised Serum Mean Platelet Volume in Patients of Ischemic and Haemorrhagic Stroke: OAJBS Publishers

Frequency of Raised Serum Mean Platelet Volume in Patients of Ischemic and Haemorrhagic Stroke by Syed Muhammad Hussain Zaidi in Open Access Journal of Biomedical Science

 

Introduction: Stroke is the second most common cause of death worldwide and is defined as cell death due to interrupted or poor blood supply. It may be caused by a blocked artery (ischemic stroke) or bursting of blood vessel (haemorrhagic stroke). Compared to the United states where 100 cases of stroke are reported annually per 100,000 population, the number is supposedly higher in south Asian countries mounting to a global burden of 40% of stroke related deaths. In the quest for an improved clinical approach and prognosis numerous platelet markers have been investigated in connection with arterial thrombosis and inflammation since platelets are known to play a crucial role in vascular pathologies. Mean platelet volume (MPV), an important variable in this regard is now increasingly being recognized for its clinical significance in both ischemic and haemorrhage stroke. Platelets with larger volume tend to demonstrate increased aggregation as compared to smaller platelets since they can both efficiently respond to and produce chemoattractant cytokines. This new observation has extended the appreciation of the link between stroke and elevated MPV
https://biomedscis.com/fulltext/frequency-of-raised-serum-mean-platelet-volume-in-patients-of-ischemic-and-haemorrhagic-stroke.ID.000155.php

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