Open Access Journal of Biomedical Science | Biomedscis

Sequential Development of Primary Cutaneous Anaplastic Large Cell Lymphoma Post Chemotherapy of Follicular Lymphoma by Haiying Hua* in Open Access Journal of Biomedical Science (OAJBS) We have presented a case of the coexistence of t-cell and b-cell tumors in a different anatomical location in one patient. This study aims to show the sequential development of primary cutaneous anaplastic large cell lymphoma (PC-ALCL) post-chemotherapy of follicular lymphoma (FL) in a case for the first time in the literature. A 38-year-old Chinese male presented to us with complaints of slowly progressing swelling in the inguinal on the left side in 2014. Then the patient revealed a diagnosis of follicular lymphoma for which the patient was treated with 6 cycles of R-CHOP regimen. He had a very good response to chemotherapy. He presented again with a new symptom of multiple nodular protrusions on the left cheek in June of 2015. After a complete work-up, he was diagnosed with primary cutaneous anaplas...

Evaluate the efficacy of Antimicrobial activity of aqueous extract of Nigella Sativa seeds powder on Staphylococcus Aureus by Piratheepkumar R* in Open Access Journal of Biomedical Science (OAJBS) Siddha system of medicine is the main traditional medicine which is very popular in south India and north and east Sri Lanka. In this system herbal, mineral and metal are mainly use for the medicine preparation and to treat the diseases. Each and every part of the herbs can be used for various, multiple ailments because of their different phyto constituents. In Siddha medicine system has been classified into Aga marunthu (Internal) and Pura marunthu (External) having 32 forms of medicines in each. The external remedies are very useful for topical ulcers, skin diseases like eczema, psoriasis bacterial and fungal infections. The purpose this study was Evaluate the efficacy of Antibacterial activity of aqueous extract of Nigella sativa seeds powder against Staphylococcus aureus by used disk...

The Mechanism Underlying Hanchuanshu Treatment of Asthma Based on Network Pharmacology and Biological Verification of The Effects in Smooth Muscle Cells by Zhiyong Liu* in Open Access Journal of Biomedical Science (OAJBS) Objective: To construct a molecular regulatory network of “components-core targets of smooth muscle action-pathways” for the treatment of asthma by Hanchuanshu. This model was used to explore the mechanism of its “multiple components-multiple targets-multiple pathways” network. Rat airway smooth muscle cells (ASMCs) were cultured in vitro, and the effect of Hanchuanshu on the cytokine expression of contractile and synthetic ASMCs was explored. Methods: The ADME/T calculation method was used to screen the components of Hanchuanshu for the treatment of asthma. Through network pharmacology methods, the target identification platform based on reverse pharmacophore matching was used to analyze. Predict potential targets, and a biological annotation database (DAVID) wa...

Factors Affecting Infectious Diseases Outbreaks and Possible Link with the Solar Activity by Maghrabi Abdullrahman* in Open Access Journal of Biomedical Science (OAJBS) Infectious diseases are a major global health problem and threat to human civilization. They have occurred throughout history and are a continuing threat to humanity and life on Earth. The outbreak and spread of infectious diseases depend on several factors: individual, physiological or immunological factors as well as social, economic, and environmental influences such as meteorological and/or cosmo-geophysical factors and climate change. Identifying these factors when they emergence is very important for detecting future pandemics. In this short paper, the social and environmental factors, focusing on the effects of solar activity on the infectious diseases, will be briefly reviewed and discussed. https://biomedscis.com/fulltext/factors-affecting-infectious-diseases-outbreaks-and-possible-link-with-the-solar-activi...

Low Dose Irradiation-Induced Pneumonia by Wen-Tian Lyu* in Open Access Journal of Biomedical Science (OAJBS) Introduction: Low-dose irradiation with high dose rate-induced radiation pneumonia (RP) is rare, and the machanism is not clear.  Patient concerns: A 65-year-old Chinese male patient, with a history of dust work, developed stage T4N2M0, IIIC lung cancer. He underwent four cycles of a paclitaxel plus cisplatin chemotherapeutic regimen. One month after chemotherapy, a chest CT scan revealed that the right main trachea was partially blocked, resulting in localized atelectasis.  Diagnosis: Lung Cancer; Radiation Pneumonia  Interventions: Palliative radiotherapy was conducted to relieve wheezing symptoms. Radiation doses were delivered as follows: A total of 6420 cGy in 30 fx was delivered to the blocked bronchus and another 5400 cGy in 30 fx to the gross tumor volume. The dose distribution in organs at risk revealed that the lung dose-volume for V20 and V30 were ...

Clinical Study on Prevention, Treatment and Health Management of 2019-nCoV Pneumonia in China by Jun Meng* in Open Access Journal of Biomedical Science (OAJBS) The population of our country has exceeded 1.4 billion, and the epidemic situation of NCP is very serious now, so the clinical research on prevention, treatment and health management of NCP is not very perfect. In order to perfect the clinical medical research on the prevention and treatment of NCP and health management in China, the existing clinical medical research on the prevention and treatment of NCP and health management in China is still based on the medical view of “specialization and specialization”, the negative effects of fragmentation of clinical knowledge and mechanization of clinical practice on the prevention and management of NCP have not been resolved. Based on the concept of integrative medicine, this paper puts forward a new concept of integrative medicine in clinical medical research on the prevention and tr...